Bhaktivedanta VedaBase: Śrīmad Bhāgavatam 8.22.25

yadā kadācij jīvātmā

saḿsaran nija-karmabhiḥ

nānā-yoniṣv anīśo 'yaḿ

pauruṣīḿ gatim āvrajet

SYNONYMS

yadā — when; kadācit — sometimes; jīva-ātmā — the living entity; saḿsaran — rotating in the cycle of birth and death; nija-karmabhiḥ — because of his own fruitive activities; nānā-yoniṣu — in different species of life; anīśaḥ — not independent (completely under the control of material nature); ayam — this living entity; pauruṣīm gatim — the situation of being human; āvrajet — wants to obtain.

TRANSLATION

While rotating in the cycle of birth and death again and again in different species because of his own fruitive activities, the dependent living entity, by good fortune, may happen to become a human being. This human birth is very rarely obtained.

PURPORT

The Supreme Personality of Godhead is fully independent. Thus it is not always a fact that a living being's loss of all opulence is a sign of the Supreme Lord's mercy upon him. The Lord can act any way He likes. He may take away one's opulence, or He may not. There are varieties of forms of life, and the Lord treats them according to the circumstances, as He chooses. Generally it is to be understood that the human form of life is one of great responsibility.

puruṣaḥ prakṛti-stho hi

bhuńkte prakṛtijān guṇān

kāraṇaḿ guṇa-sańgo 'sya

sad-asad-yoni-janmasu

"The living entity in material nature follows the ways of life, enjoying the three modes of nature. This is due to his association with that material nature. Thus he meets with good and evil amongst various species." (Bg. 13.22) After thus rotating through many, many forms of life in the cycle of birth and death, the living being gets a chance for a human form. Therefore every human being, especially one belonging to a civilized nation or culture, must be extremely responsible in his activities. He should not risk degradation in the next life. Because the body will change (tathā dehāntara-prāptir), we should be extremely careful. To see to the proper use of life is the purpose of Kṛṣṇa consciousness. The foolish living entity declares freedom from all control, but factually he is not free; he is fully under the control of material nature. He must therefore be most careful and responsible in the activities of his life.

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His Divine Grace A. C. Bhaktivedanta Swami Prabhupāda, Founder Ācārya of the International Society for Krishna Consciousness